A Novel Plated Hepatocyte Relay Assay (PHRA) for In Vitro Evaluation of Hepatic Metabolic Clearance of Slowly Metabolized Compounds

Publisher： Bentham Science Publishers

E-ISSN： 1874-0758|10|1|3-15

ISSN： 1872-3128

Source： Drug Metabolism Letters, Vol.10, Iss.1, 2016-03, pp. : 3-15

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

Prediction of Human Hepatic Clearance Using an In Vitro Plated Hepatocyte Clearance Model

By  

Drug Metabolism Letters, Vol. 3, Iss. 4, 2009-12 ,pp. : 296-307

Bentham Science Publishers

Access to resources Recommend Favorite

An Estimate of the Number of Hepatocyte Donors Required to Provide Reasonable Estimates of Human Hepatic Clearance from In Vitro Experiments

By  

Drug Metabolism Letters, Vol. 1, Iss. 2, 2007-01 ,pp. : 91-95

Bentham Science Publishers

Access to resources Recommend Favorite

On the maintenance of hepatocyte intracellular pH 7.0 in the in-vitro metabolic stability assay

By Berezhkovskiy Leonid   Wong Susan   Halladay Jason  

Journal of Pharmacokinetics and Pharmacodynamics, Vol. 40, Iss. 6, 2013-12 ,pp. : 683-689

Springer Publishing Company

Access to resources Recommend Favorite

Prediction of Hepatic Metabolic Clearance Based on Interspecies Allometric Scaling Techniques and In Vitro - In Vivo Correlations

By Lavé T.  

Clinical Pharmacokinetics, Vol. 36, Iss. 3, 1999-03 ,pp. : 211-231

Adis International

Access to resources Recommend Favorite

Novel In Vitro-In Vivo Extrapolation (IVIVE) Method to Predict Hepatic Organ Clearance in Rat

By Umehara Ken-ichi   Camenisch Gian  

Pharmaceutical Research, Vol. 29, Iss. 2, 2012-02 ,pp. : 603-617

Springer Publishing Company

Access to resources Recommend Favorite