Publisher： Karger
E-ISSN： 1424-859x|103|1-2|3-7
ISSN： 1424-8581
Source： Cytogenetic and Genome Research, Vol.103, Iss.1-2, 2004-03, pp. : 3-7
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
The structural rearrangement in the short arm of a chromosome 8 in a clinically affected patient has been reinvestigated by FISH using whole chromosome painting and region specific YAC probes. An inverted duplication of the segment p22→p11.2 and a deletion of the subtelomeric region were demonstrated. By this approach, a more detailed resolution of the duplication/deletion 8p was possible. With the application of molecular cytogenetic methods the existence of different duplication segments within the clinical entity of duplication/deficiency 8p can be shown.
Related content
Access to resources
Recommend
8p11 Myeloproliferative Syndrome with t(1;8)(q25;p11.2): A Case Report and Review of the Literature
Acta Haematologica, Vol. 133, Iss. 1, 2014-09 ,pp. :