Publisher: Karger
E-ISSN: 1421-9794|46|1|62-68
ISSN: 0009-3157
Source: Chemotherapy, Vol.46, Iss.1, 1999-12, pp. : 62-68
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Abstract
Yuehchukene (YCK) is a novel bis-indole alkaloid with weak estrogenic activity. Biochemical studies showed that YCK could attenuate estrogenic action. In this study, the response of MCF-7, an estrogen-receptor-positive breast cancer cell line, under different combinations of estradiol, cyclophosphamide and YCK, was tested. From the dose-response curve, we discovered that 10–2
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