Littoral Cell Angioma Associated with Portal Hypertension and Resected Colon Cancer

Publisher: Karger

E-ISSN: 1421-9662|104|2-3|131-134

ISSN: 0001-5792

Source: Acta Haematologica, Vol.104, Iss.2-3, 2001-01, pp. : 131-134

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Littoral cell angioma (LCA) is a rare vascular tumor of the spleen with an unknown etiology and unclear natural history. An association with synchronous malignancy has been described. We report the case of a 54-year-old woman who had progressive splenomegaly over 3 years following resection of a colon adenocarcinoma. The splenomegaly was associated with portal hypertension and severe thrombocytopenia. Splenectomy was performed, and the histologic and immunocytochemical features of the spleen specimen were consistent with LCA. The relationship between LCA and malignancy is reviewed.