Acute Liver Failure Associated with Propylthiouracil in a Pregnant 26-Year-Old Woman

Publisher: Karger

E-ISSN: 1662-0631|7|2|240-244

ISSN: 1662-0631

Source: Case Reports in Gastroenterology, Vol.7, Iss.2, 2013-05, pp. : 240-244

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Abstract

It seems appropriate to use propylthiouracil to treat maternal hyperthyroidism during the first trimester of pregnancy. We present the case of a 26-year-old woman with acute liver failure associated with propylthiouracil during the first trimester of pregnancy. She was successfully treated without liver transplantation. Attention should be paid to the possible occurrence of propylthiouracil-induced hepatotoxicity even during the first trimester of pregnancy.