Publisher： Karger
E-ISSN： 1421-9921|32|2|107-110
ISSN： 0014-312x
Source： European Surgical Research, Vol.32, Iss.2, 2000-05, pp. : 107-110
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Abstract
Previous work from our laboratory demonstrated the feasibility of utilizing placental-derived collagen tissue matrix (CTM) as a bowel wall substitute. We reasoned that this technique would also be suitable in managing intestinal fistulae. To test this hypothesis, we created a chronic cecal fistula in rats and randomly managed some with primary repair and others with CTM replacement. Leak rates, mortality, bursting pressures and histologic scores were similar, suggesting that a chronic fistula can be successfully managed with either a CTM or primary repair.
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