Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry: New Technology for Vascular Pathology

Publisher： Karger

E-ISSN： 1423-0135|51|2|144-148

ISSN： 1018-1172

Source： Journal of Vascular Research, Vol.51, Iss.2, 2014-05, pp. : 144-148

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Abstract

The use of matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) for the assessment of vascular pathology is attracting attention as a new valuable tool for diagnosing disease and finding new markers. MALDI-IMS is a molecular imaging technique whereby the simultaneous measurement of multiple samples directly from clinical tissue sections is possible. The versatility of MALDI-IMS has opened a new frontier in vascular pathology. In this review, we describe the principle and applications of MALDI-IMS.

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