Functional and Morphological Changes after Macular Pucker Surgery: An Optical Coherence Tomography and Microperimetric Study

Publisher： Karger

E-ISSN： 1423-0267|232|4|200-206

ISSN： 0030-3755

Source： Ophthalmologica, Vol.232, Iss.4, 2014-10, pp. : 200-206

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Abstract

Purpose: To investigate the relationship among functional and morphological findings before and after macular pucker surgery. Methods: Thirty-eight eyes with idiopathic macular pucker that underwent 25-gauge vitrectomy and infracyanine green-assisted internal limiting membrane peeling were prospectively enrolled. Main outcome measures were best-corrected visual acuity (BCVA), spectral-domain optical coherence tomography findings and MP-1 microperimetry findings. Results: Mean BCVA improvement was 0.34 logMAR (p < 0.0001). Mean central retinal thickness (CRT) reduction was 50 µm (p = 0.0041). Mean retinal sensitivity improvement was 0.9. Patients with a greater improvement of postoperative BCVA showed worse baseline BCVA (p < 0.001), shorter final inner/outer segment (IS/OS) interruption length (p = 0.039) and thinner final CRT (p = 0.035). Furthermore, final BCVA was correlated with baseline IS/OS interruption length (p = 0.001). Conclusion: Baseline BCVA, CRT and IS/OS integrity can be used to predict the functional outcomes after macular pucker surgery.