Nrf2/ARE通路与器官缺血再灌注损伤

Publisher: 国家哲学社会科学学术期刊数据库

E-ISSN: 1008-293x|36|7|100-104

ISSN: 1008-293x

Source: 绍兴文理学院学报, Vol.36, Iss.7, 2016-01, pp. : 100-104

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Abstract

随着医学技术的提高,对Nrf2/ARE通路在器官缺血再灌注损伤中作用的研究不断深入,逐步阐明了Nrf2/ARE通路与器官缺血再灌注损伤的关系.氧化应激是器官缺血再灌注损伤的最重要机制,而Nrf2是内源性细胞抗氧化应激的关键因子,Nrt2/ARE通路的激活,可以较好地改善器官缺血再灌注损伤状况.