Approach to the prediction of the contribution of major cytochrome P450 enzymes to drug metabolism in the early drug-discovery stage

By Emoto C.   Murase S.   Iwasaki K.  

Xenobiotica, Vol. 36, Iss. 8, 2006-08 ,pp. : 671-683

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Approach to predict the contribution of cytochrome P450 enzymes to drug metabolism in the early drug-discovery stage: The effect of the expression of cytochrome b5 with recombinant P450 enzymes

By Emoto C.   Iwasaki K.  

Xenobiotica, Vol. 37, Iss. 9, 2007-09 ,pp. : 986-999

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Mechanism-based inactivation of human cytochrome P450 enzymes: strategies for diagnosis and drug–drug interaction risk assessment

By Venkatakrishnan K.   Obach R. S.   Rostami-Hodjegan A.  

Xenobiotica, Vol. 37, Iss. 10-11, 2007-11 ,pp. : 1225-1256

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Drug-drug interactions in the metabolism of imidafenacin: Role of the human cytochrome P450 enzymes and UDP-glucuronic acid transferases, and potential of imidafenacin to inhibit human cytochrome P450 enzymes

By Kanayama N.   Kanari C.   Masuda Y.   Ohmori S.   Ooie T.  

Xenobiotica, Vol. 37, Iss. 2, 2007-02 ,pp. : 139-154

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Identification of cytochrome P450 enzymes involved in the metabolism of 3',4'-methylenedioxy- a -pyrrolidinopropiophenone (MDPPP), a designer drug, in human liver microsomes

By Springer D   Staack R. F   Paul L. D   Kraemer T   Maurer H. H  

Xenobiotica, Vol. 35, Iss. 3, 2005-03 ,pp. : 227-237

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