Molecular, Cellular, and Epigenetic Signatures of Prostaglandin E2 in Endometriosis

Publisher： Bentham Science Publishers

E-ISSN： 1875-6581|14|2|127-146

ISSN： 1573-4048

Source： Current Women's Health Reviews, Vol.14, Iss.2, 2018-04, pp. : 127-146

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Background: Endometriosis is a debilitating and chronic inflammatory gynecologicaldisease of reproductive age women. Two major clinical symptoms of endometriosis are chronicpelvic pain and infertility, which profoundly affect the quality of life in women. Current treatmentstrategies include surgical intervention, anti-estrogen hormonal therapy, or a combination of both.The existing treatment modalities fail to prevent recurrence of disease and affect reproductivehealth of women. This suggests a fundamental need to identify potential cell signaling pathways fornonestrogen or nonsteroidal targets for endometriosis. A growing body of evidence indicates thatgrowth factors, cytokines, and prostaglandins promote the establishment and maintenance of endometriosis.lt;/Pgt

Related content

Molecular and Cellular Pathogenesis of Endometriosis

By  

Current Women's Health Reviews, Vol. 14, Iss. 2, 2018-04 ,pp. : 106-116 (11)

Bentham Science Publishers

Access to resources Recommend Favorite

Editorial: Clinical, Cellular and Molecular Aspects of Endometriosis

By  

Current Women's Health Reviews, Vol. 14, Iss. 2, 2018-04 ,pp. : 87-87 (1)

Bentham Science Publishers

Access to resources Recommend Favorite

Prostaglandin E‐mediated molecular mechanisms driving remodeling of the ductus arteriosus

By  

PEDIATRICS INTERNATIONAL, Vol. 57, Iss. 5, 2015-10 ,pp. : 820-827 (8)

John Wiley & Sons Inc

Access to resources Recommend Favorite

The role of cyclooxygenase‐2 and prostaglandin E2 in the pathogenesis of cutaneous lichen planus

By  

CLINICAL & EXPERIMENTAL DERMATOLOGY, Vol. 40, Iss. 8, 2015-12 ,pp. : 903-907 (5)

John Wiley & Sons Inc

Access to resources Recommend Favorite

EFFECT OF THYROXINE ON THE CONTRACTILE RESPONSES OF THE VAS DEFERENS TO PROSTAGLANDIN E2

By Amadi K.   Nwana E. J. C.   Otubu J. A. M.  

Archives of Andrology, Vol. 42, Iss. 2, 1999-03 ,pp. : 55-62 (8)

Informa Healthcare

Access to resources Recommend Favorite