In Vitro and In Vivo Performance of Novel Spray Dried Andrographolide Loaded Scleroglucan Based Formulation for Dry Powder Inhaler

Publisher: Bentham Science Publishers

E-ISSN: 1875-5704|14|7|968-980

ISSN: 1567-2018

Source: Current Drug Delivery, Vol.14, Iss.7, 2017-10, pp. : 968-980

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Abstract

Background: Current therapy for pulmonary arterial hypertension (PAH) is unable to preventprogression of disease due to continuous infusions and multiple oral administrations. This resultedin the need of novel treatment which would target directly structural vascular changes that weakenblood flow through pulmonary circulation.lt;/Pgt