Lipid Based Anti-Retroviral Nanocarriers: A Review of Current Literature and Ongoing Studies

Publisher： Bentham Science Publishers

E-ISSN： 2210-304x|7|2|71-82

ISSN： 2210-3031

Source： Drug Delivery Letters, Vol.7, Iss.2, 2017-08, pp. : 71-82

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Abstract

Background: The invention of an efficacious drug delivery system for the treatment ofHIV/AIDS still remains a worldwide problem and presently, an ideal remedy for HIV/AIDS is notavailable. One of the greatest achievements in transforming HIV infection into a chronically manageddisease is anti-retroviral therapy (ART) including Highly Active Antiretroviral Therapy(HAART) which has increased the life span and improved the quality of life of the HIV/AIDS patient.But, the lack of widespread preventive measures and the inability of anti-retroviral (ARV)drugs to eliminate HIV from infected cells still remain a challenge. Also, the current ARVs are unableto reach the HIV viral load present in the brain which is one of the important sanctuary sites forthe HIV virus.lt;Pgt

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