Visible‐Light, Metal‐Free α‐Amino C(sp3)–H Activation through 1,5‐Hydrogen Migration: A Concise Method for the Preparation of Bis(indolyl)alkanes

Publisher： John Wiley & Sons Inc

E-ISSN： 1099-0690|2015|35|7643-7647

ISSN： 1434-193x

Source： EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Vol.2015, Iss.35, 2015-12, pp. : 7643-7647

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Abstract

AbstractA photoredox catalytic, metal‐free method for C–H functionalization α to amines directly leads to the formation of bis(indolyl)alkane products in good to excellent yields. This transformation hinges on a smooth 1,5‐hydrogen migration to an aryl radical intermediate.

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