Publisher: Cambridge University Press
E-ISSN: 1475-2662|101|2|169-181
ISSN: 0007-1145
Source: British Journal of Nutrition, Vol.101, Iss.2, 2009-01, pp. : 169-181
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Abstract
Damage of the intestinal epithelial barrier by xenobiotics or reactive oxygen species and a dysregulated immune response are both factors involved in the pathogenesis of inflammatory bowel diseases (IBD). Curcumin and rutin are polyphenolic compounds known to have antioxidant and anti-inflammatory activities, but their mechanism(s) of action are yet to be fully elucidated. Multidrug resistance gene-deficient (
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