Publisher: Cambridge University Press
E-ISSN: 1475-2662|106|2|213-217
ISSN: 0007-1145
Source: British Journal of Nutrition, Vol.106, Iss.2, 2011-07, pp. : 213-217
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Abstract
Autophagy, a catabolic process responsible for the degradation of cytosolic components and the preservation of cellular homeostasis in virtually all eukaryotic organisms, is up-regulated when nutrient supplies are limited. However, whether early weaning induces autophagy in infants is not completely clear. In the present study, we used piglets as the early-weaning model to examine the autophagic activity in different tissues in response to nutrient status. Western blot analysis demonstrated that microtubule-associated protein 1 light chain 3-II, a promising marker protein for macroautophagy, was expressed at a notably higher level at 12 and 24 h weaning treatments than without weaning treatment (
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