In Vivo MRI and X‐Ray Bifunctional Imaging of Polymeric Composite Supplemented with GdPO4·H2O Nanobundles for Tracing Bone Implant and Bone Regeneration

Publisher: John Wiley & Sons Inc

E-ISSN: 2192-2659|5|17|2182-2190

ISSN: 2192-2640

Source: ADVANCED HEALTHCARE MATERIALS (ELECTRONIC), Vol.5, Iss.17, 2016-09, pp. : 2182-2190

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Homogeneous and monodisperse GdPO4·H2O nanobundles are successfully synthesized via a solvothermal method. Then, GdPO4·H2O are incorporated into the composite of hydroxyapatite and poly(lactic‐co‐glycolic acid) to obtain a biodegradable and traceable bone implant. After implanted, the GdPO4·H2O/HA/PLGA implant and the newly formed bone can be easily traced and observed through the combination of magnetic resonance imaging and X‐ray imaging.