Synthesis of (2R,3S)-((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl) 2-(4-bromophenyl)-3-(tert-butoxycarbonylamino)-tetrahydrofuran-3-carboxylate and (2S,3R)-((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl) 2-(4-bromophenyl)-3-(tert-butoxycarbonylamino)-tetrahydrofuran-3-carboxylate

Author： Grauer Andreas   König Burkhard  

Publisher： MDPI

E-ISSN： 1422-8599|2009|1|M594-M594

ISSN： 1422-8599

Source： Molbank, Vol.2009, Iss.1, 2009-03, pp. : M594-M594

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Abstract

Two new Cα-tetrasubstituted α-amino acids (2R,3S)-((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl) 2-(4-bromophenyl)-3-(tert-butoxycarbonylamino)-tetrahydrofuran-3-carboxylate and (2S,3R)-((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl) 2-(4-bromophenyl)-3-(tert-butoxycarbonylamino)-tetrahydrofuran-3-carboxylate were synthesized and characterized by NMR, MS, elemental analysis and X-ray.

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