

Author: Youngstrom Eric LaKind Judy S. Kenworthy Lauren Lipkin Paul H. Goodman Michael Squibb Katherine Mattison Donald R. Anthony Bruno J. Anthony Laura Gutermuth
Publisher: MDPI
E-ISSN: 1660-4601|7|1|229-268
ISSN: 1660-4601
Source: International Journal of Environmental Research and Public Health, Vol.7, Iss.1, 2010-01, pp. : 229-268
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
With research suggesting increasing incidence of pediatric neurodevelopmental disorders, questions regarding etiology continue to be raised. Neurodevelopmental function tests have been used in epidemiology studies to evaluate relationships between environmental chemical exposures and neurodevelopmental deficits. Limitations of currently used tests and difficulties with their interpretation have been described, but a comprehensive critical examination of tests commonly used in studies of environmental chemicals and pediatric neurodevelopmental disorders has not been conducted. We provide here a listing and critical evaluation of commonly used neurodevelopmental tests in studies exploring effects from chemical exposures and recommend measures that are not often used, but should be considered. We also discuss important considerations in selecting appropriate tests and provide a case study by reviewing the literature on polychlorinated biphenyls.
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