Biological Activities of Polyphenols from Grapes

Author： Xia En-Qin Deng Gui-Fang Guo Ya-Jun Li Hua-Bin

Publisher： MDPI

E-ISSN： 1422-0067|11|2|622-646

ISSN： 1422-0067

Source： International Journal of Molecular Sciences, Vol.11, Iss.2, 2010-02, pp. : 622-646

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Abstract

The dietary consumption of grape and its products is associated with a lower incidence of degenerative diseases such as cardiovascular disease and certain types of cancers. Most recent interest has focused on the bioactive phenolic compounds in grape. Anthocyanins, flavanols, flavonols and resveratrol are the most important grape polyphenols because they possess many biological activities, such as antioxidant, cardioprotective, anticancer, anti-inflammation, antiaging and antimicrobial properties. This review summarizes current knowledge on the bioactivities of grape phenolics. The extraction, isolation and identification methods of polyphenols from grape as well as their bioavailability and potential toxicity also are included.