Author： Choulier Laurence Enander Karin
Publisher： MDPI
E-ISSN： 1424-8220|10|4|3126-3144
ISSN： 1424-8220
Source： Sensors, Vol.10, Iss.4, 2010-03, pp. : 3126-3144
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Abstract
Biosensors allow the direct detection of molecular analytes, by associating a biological receptor with a transducer able to convert the analyte-receptor recognition event into a measurable signal. We review recent work aimed at developing synthetic fluorescent molecular sensors for a variety of analytes, based on peptidic receptors labeled with environmentally sensitive fluorophores. Fluorescent indicators based on synthetic peptides are highly interesting alternatives to protein-based sensors, since they can be synthesized chemically, are stable, and can be easily modified in a site-specific manner for fluorophore coupling and for immobilization on solid supports.
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