Author: Stanford Clark M.
Publisher: MDPI
E-ISSN: 1422-0067|11|1|354-369
ISSN: 1422-0067
Source: International Journal of Molecular Sciences, Vol.11, Iss.1, 2010-01, pp. : 354-369
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
Bone adaptation or integration of an implant is characterized by a series of biological reactions that start with bone turnover at the interface (a process of localized necrosis), followed by rapid repair. The wound healing response is guided by a complex activation of macrophages leading to tissue turnover and new osteoblast differentiation on the implant surface. The complex role of implant surface topography and impact on healing response plays a role in biological criteria that can guide the design and development of future tissue-implant surface interfaces.
Related content
By Reinders Yvonne Felthaus Oliver Brockhoff Gero Pohl Fabian Ahrens Norbert Prantl Lukas Haubner Frank
International Journal of Molecular Sciences, Vol. 18, Iss. 8, 2017-08 ,pp. :