Author： Wang Li-qin Yu Xue-wen Yan Chun-fang Wang Xiang
Publisher： MDPI
E-ISSN： 1422-0067|11|2|521-531
ISSN： 1422-0067
Source： International Journal of Molecular Sciences, Vol.11, Iss.2, 2010-02, pp. : 521-531
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
The nuclear factor kappa B is widely expressed in the distinct subpopulations of chorionic villi and deciduas of first-trimester pregnancies. We examined the cellular distribution and expression of nuclear factor kappa B in the human first-trimester chorionic villi and deciduas of women with early spontaneous miscarriage and viable pregnancy by confocal laser scanning microscope and immunohistochemistry. There is a greater nuclear translocation of nuclear factor kappa B is restricted to villous stromal cells, decidual stromal cells, glandular epithelial cells and vessel endothelial cells in early spontaneous miscarriage than in viable pregnancies. Collectively these observations suggest that over-activation of nuclear factor kappa B has a relationship with early spontaneous miscarriages.
Related content
Access to resources
Recommend
By Xiao Wen Qin Yin Guo Jian Fan Yu Ting Qiu Lei Cang Xiao Feng Yu Ge Hu Yan Ling Xing Miao Wu De Qing Wang Xing Peng Hu Guo Yong Wan Rong
International Journal of Molecular Sciences, Vol. 15, Iss. 7, 2014-07 ,pp. :
By Tiangco David A. Halcomb Sapna Lattanzio Frank A. Hargrave Barbara Y.
International Journal of Molecular Sciences, Vol. 11, Iss. 12, 2010-11 ,pp. :
By Kanazawa Takanori Shizawa Yuki Takeuchi Mayu Tamano Kuniko Ibaraki Hisako Seta Yasuo Takashima Yuuki Okada Hiroaki
Pharmaceutics, Vol. 7, Iss. 3, 2015-09 ,pp. :
By Li Haining Chen Guisheng Ma Wanrui Li Ping-An Andy
International Journal of Molecular Sciences, Vol. 15, Iss. 8, 2014-07 ,pp. :