Development of Biomedical Polymer-Silicate Nanocomposites: A Materials Science Perspective

Author： Wu Chia-Jung Gaharwar Akhilesh K. Schexnailder Patrick J. Schmidt Gudrun

Publisher： MDPI

E-ISSN： 1996-1944|3|5|2986-3005

ISSN： 1996-1944

Source： Materials, Vol.3, Iss.5, 2010-04, pp. : 2986-3005

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Abstract

Biomedical polymer-silicate nanocomposites have potential to become critically important to the development of biomedical applications, ranging from diagnostic and therapeutic devices, tissue regeneration and drug delivery matrixes to various bio-technologies that are inspired by biology but have only indirect biomedical relation. The fundamental understanding of polymer-nanoparticle interactions is absolutely necessary to control structure-property relationships of materials that need to work within the chemical, physical and biological constraints required by an application. This review summarizes the most recent published strategies to design and develop polymer-silicate nanocomposites (including clay based silicate nanoparticles and bioactive glass nanoparticles) for a variety of biomedical applications. Emerging trends in bio-technological and biomedical nanocomposites are highlighted and potential new fields of applications are examined.