Author： Leyten Gisele H. J. M. Wierenga Elisabeth A. Michiel Sedelaar J. P. van Oort Inge M. Futterer Jurgen J. Barentsz Jelle O. Schalken Jack A. Mulders Peter F. A.
Publisher： MDPI
E-ISSN： 1422-0067|14|6|11347-11355
ISSN： 1422-0067
Source： International Journal of Molecular Sciences, Vol.14, Iss.6, 2013-05, pp. : 11347-11355
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
PCA3 (prostate cancer gene 3) and multiparametric 3 tesla MRI are new promising diagnostic tools in the detection of PCa. Our aim was to study the clinical value of the Progensa PCA3-test: its predictive value for biopsy outcome, Gleason score and MRI outcome. We evaluated, retrospectively, 591 patients who underwent a Progensa PCA3-test at the Radboud University Nijmegen Medical Centre between May 2006 and December 2009. Prostate biopsies were performed in 290 patients; a multiparametric 3 tesla MRI of the prostate was performed in 163/591 patients. The PCA3-score was correlated to biopsy results and MRI outcome. The results show that PCA3 was highly predictive for biopsy outcome (
Related content
Access to resources
Recommend
By Yan Fang Luo Shaojie Jiao Yu Deng Yuewen Du Xiaodong Huang Ronglian Wang Qingheng Chen Weiyao
International Journal of Molecular Sciences, Vol. 15, Iss. 11, 2014-11 ,pp. :