Author: Yu Dangfan Du Kaiqi Liu Taifeng Chen Guojun
Publisher: MDPI
E-ISSN: 1422-0067|14|6|11145-11156
ISSN: 1422-0067
Source: International Journal of Molecular Sciences, Vol.14, Iss.6, 2013-05, pp. : 11145-11156
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Abstract
The aim of this study was to investigate the prognostic value of tumor markers in operable non-small cell lung cancer (NSCLC) patients. A total of 481 NSCLC patients were enrolled in the present study. High levels of neuron-specific enolase (NSE), carbohydrate antigen 125 (CA125) and squamous cell carcinoma antigen (SCC) were detected in 306 (63.6%), 89 (18.5%) and 125 (26.0%) patients, respectively. Seventy-eight of 481 patients died of disease progression, and the median disease-free survival (DFS) and overall survival (OS) were 16.0 and 21.0 months, respectively. The three-year DFS rate was 56.7%, and the OS rate was 75.3%. For serum NSE, the three-year cumulative DFS rate for the normal and elevated group was 67.7% and 51.8% (
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