Biomimetic Adhesive Materials Containing Cyanoacryl Group for Medical Application

Author: Jo Sueng Hwan   Sohn Jeong Sun  

Publisher: MDPI

E-ISSN: 1420-3049|19|10|16779-16793

ISSN: 1420-3049

Source: Molecules, Vol.19, Iss.10, 2014-10, pp. : 16779-16793

Access to resources Favorite

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

For underwater adhesives with biocompatible and more flexible bonds using biomimetic adhesive groups, DOPA-like adhesive molecules were modified with cyanoacrylates to obtain different repeating units and chain length copolymers. The goal of this work is to copy the mechanisms of underwater bonding to create synthetic water-borne underwater medical adhesives through blending of the modified DOPA and a triblock copolymer (PEO-PPO-PEO) for practical application to repair wet living tissues and bones, and in turn, to use the synthetic adhesives to test mechanistic hypotheses about the natural adhesive. The highest values in stress and modulus of the biomimetic adhesives prepared in wet state were 165 kPa and 33 MPa, respectively.

Related content