

Author: Ouyang Hong Goldberg Jeffrey L. Chen Shuyi Li Wei Xu Guo-Tong Li Wei Zhang Kang Nussenblatt Robert B. Liu Yizhi Xie Ting Chan Chi-Chao Zack Donald J.
Publisher: MDPI
E-ISSN: 1422-0067|17|3|415-415
ISSN: 1422-0067
Source: International Journal of Molecular Sciences, Vol.17, Iss.3, 2016-03, pp. : 415-415
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
Stem cells hold promise for treating a wide variety of diseases, including degenerative disorders of the eye. The eye is an ideal organ for stem cell therapy because of its relative immunological privilege, surgical accessibility, and its being a self-contained system. The eye also has many potential target diseases amenable to stem cell-based treatment, such as corneal limbal stem cell deficiency, glaucoma, age-related macular degeneration (AMD), and retinitis pigmentosa (RP). Among them, AMD and glaucoma are the two most common diseases, affecting over 200 million people worldwide. Recent results on the clinical trial of retinal pigment epithelial (RPE) cells from human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) in treating dry AMD and Stargardt’s disease in the US, Japan, England, and China have generated great excitement and hope. This marks the beginning of the ocular stem cell therapy era. The recent Zhongshan Ophthalmic Center Ocular Stem Cell Symposium discussed the potential applications of various stem cell types in stem cell-based therapies, drug discoveries and tissue engineering for treating ocular diseases.
Related content


Recent Updates on Treatment of Ocular Microbial Infections by Stem Cell Therapy: A Review
By Teh Seoh Wei Mok Pooi Ling Abd Rashid Munirah Bastion Mae-Lynn Catherine Ibrahim Normala Higuchi Akon Murugan Kadarkarai Mariappan Rajan Subbiah Suresh Kumar
International Journal of Molecular Sciences, Vol. 19, Iss. 2, 2018-02 ,pp. :


Regenerative Medicine for Epilepsy: From Basic Research to Clinical Application
By Yasuhara Takao Agari Takashi Kameda Masahiro Kondo Akihiko Kuramoto Satoshi Jing Meng Sasaki Tatsuya Toyoshima Atsuhiko Sasada Susumu Sato Kenichiro Shinko Aiko Wakamori Takaaki Okuma Yu Miyoshi Yasuyuki Tajiri Naoki Borlongan Cesario V. Date Isao
International Journal of Molecular Sciences, Vol. 14, Iss. 12, 2013-11 ,pp. :






By Reikvam Håkon Fredly Hanne Kittang Astrid Olsnes Bruserud Øystein
Toxins, Vol. 5, Iss. 2, 2013-02 ,pp. :