Publisher: John Wiley & Sons Inc
E-ISSN: 1099-0690|2015|18|3957-3962
ISSN: 1434-193x
Source: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Vol.2015, Iss.18, 2015-06, pp. : 3957-3962
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
AbstractHeterocyclic fused α‐methylene β‐lactams were successfully synthesized by a post‐Ugi InIII‐catalyzed intramolecular addition reaction. Switching from InCl3 to AlCl3 led to the regioselective synthesis of α,β‐unsaturated γ‐lactams. Moreover, replacing terminal alkynes by substituted alkynes in the Ugi adducts resulted in the exclusive formation of γ‐lactams with both catalytic systems.
Related content
Two‐Step Synthesis of Multifunctional γ‐Lactams from γ‐Lactone
JOURNAL OF HETEROCYCLIC CHEMISTRY, Vol. 52, Iss. 5, 2015-09 ,pp. :
Two‐Step Synthesis of Multifunctional γ‐Lactams from γ‐Lactone
JOURNAL OF HETEROCYCLIC CHEMISTRY, Vol. 22-152X, Iss. 5, 2015-09 ,pp. :
Chiral γ‐Lactams by Enantioselective Palladium(0)‐Catalyzed Cyclopropane Functionalizations
ANGEWANDTE CHEMIE, Vol. 127, Iss. 40, 2015-09 ,pp. :