

Publisher: John Wiley & Sons Inc
E-ISSN: 1439-7633|16|15|2114-2114
ISSN: 1439-4227
Source: CHEMBIOCHEM, Vol.16, Iss.15, 2015-10, pp. : 2114-2114
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
The inside cover picture shows the key areas of atomic structural change that occurs within the carbohydrate‐recognition domain (VP8*) of human rotavirus K8 upon binding to A‐type human blood group antigen. These are the first reported data that reveal significant rotavirus VP8* structural changes upon glycan binding and provide evidence for VP8* adaptability to different host glycan receptors, which might have implications for cross‐species infection.