Publisher： John Wiley & Sons Inc
E-ISSN： 1943-5193|52|6|1806-1811
ISSN： 0022-152x
Source： JOURNAL OF HETEROCYCLIC CHEMISTRY, Vol.52, Iss.6, 2015-11, pp. : 1806-1811
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
A simple and straight forward solvent free method for the synthesis of a series of highly functionalized tetrahydropyridine derivatives has been achieved via multicomponent reaction of aromatic aldehydes, various amines, and β‐keto esters at room temperature using readily available (±)‐camphor‐10‐sulfonic acid as an organocatalyst. The current protocol offers an atom economic and environmentally benign method for the synthesis of the title compounds under solvent free conditions in good yields with high substrate scope and avoids column chromatographic purification.
Related content
By Habibi Azizollah Mousavifar Leyla Yavari Issa Yazdanbakhsh Mohammad R.
Monatshefte für Chemie / Chemical Monthly, Vol. 138, Iss. 6, 2007-06 ,pp. :
Access to resources
Recommend
