Improved motion contrast and processing efficiency in OCT angiography using complex-correlation algorithm

Author: Guo Li   Li Pei   Pan Cong   Liao Rujia   Cheng Yuxuan   Hu Weiwei   Chen Zhong   Ding Zhihua   Li Peng  

Publisher: IOP Publishing

E-ISSN: 2040-8986|18|2|25301-25311

ISSN: 2040-8986

Source: Journal of Optics, Vol.18, Iss.2, 2016-02, pp. : 25301-25311

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Abstract

The complex-based OCT angiography (Angio-OCT) offers high motion contrast by combining both the intensity and phase information. However, due to involuntary bulk tissue motions, complex-valued OCT raw data are processed sequentially with different algorithms for correcting bulk image shifts (BISs), compensating global phase fluctuations (GPFs) and extracting flow signals. Such a complicated procedure results in massive computational load. To mitigate such a problem, in this work, we present an inter-frame complex-correlation (CC) algorithm. The CC algorithm is suitable for parallel processing of both flow signal extraction and BIS correction, and it does not need GPF compensation. This method provides high processing efficiency and shows superiority in motion contrast. The feasibility and performance of the proposed CC algorithm is demonstrated using both flow phantom and live animal experiments.