Cobalt‐Catalyzed Diborylation of 1,1‐disubstituted Vinylarenes: A Practical Route to Branched gem‐Bis(boryl)alkanes

Publisher： John Wiley & Sons Inc

E-ISSN： 1521-3757|130|6|1670-1674

ISSN： 0044-8249

Source： ANGEWANDTE CHEMIE, Vol.130, Iss.6, 2018-02, pp. : 1670-1674

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Abstract

AbstractWe report the first catalytic diborylation of 1,1‐disubstituted vinylarenes with pinacolborane using a cobalt catalyst generated from bench‐stable Co(acac)2 and xantphos. A wide range of 1,1‐disubstituted vinylarenes underwent this transformation to produce the corresponding gem‐bis(boryl)alkanes in modest to high yields. This cobalt‐catalyzed reaction can be readily conducted on a gram scale without the use of a dry box and represents a practical and effective approach to prepare a wide range of branched gem‐bis(boryl)alkanes.

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