Publisher： John Wiley & Sons Inc
E-ISSN： 1099-0690|2018|6|815-820
ISSN： 1434-193x
Source： EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Vol.2018, Iss.6, 2018-02, pp. : 815-820
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
The Chan–Lam coupling reaction starting from phenyldithiocarbamates and phenylboronic acids is reported. To avoid using the volatile, hazardous, and foul‐smelling thiols, which are sometimes expensive and not sufficiently available, phenyldithiocarbamates can be employed. They are demonstrated to be good sulfuration reagents in the Chan–Lam coupling to prepare biaryl sulfides. By using this protocol, dithiocarbamate substrates with a wide range of functional groups including electron‐rich and electron‐deficient ones are explored to obtain the desired substituted biaryl sulfides smoothly. This method is ligand‐free, has a broad substrate scope, enables good yields, and is easy to perform. It provides a facile and convenient preparation of biaryl sulfides.
Related content
Visible‐Light‐Mediated Chan–Lam Coupling Reactions of Aryl Boronic Acids and Aniline Derivatives
ANGEWANDTE CHEMIE, Vol. 127, Iss. 22, 2015-05 ,pp. :
Access to resources
Recommend
