Author： Xiong Jian
Publisher： Springer Publishing Company
ISSN： 0168-9673
Source： Acta Mathematicae Applicatae Sinica, Vol.23, Iss.3, 2007-07, pp. : 467-476
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
A shrinkage estimator and a maximum likelihood estimator are proposed in this paper for combination of bioassays. The shrinkage estimator is obtained in closed form which incorporates prior information just on the common log relative potency after the homogeneity test for combination of bioassays is accepted. It is a practical improvement over other estimators which require iterative procedure to obtain the estimator for the relative potency. A real data is also used to show the superiorities for the newly-proposed procedures. Keywords 2000 MR Subject Classification
Related content
Access to resources
Recommend
High Throughput Bioassays Using Nanoparticles
Combinatorial Chemistry & High Throughput Screening, Vol. 13, Iss. 4, 2010-05 ,pp. :
A New Estimator for a Tail Index
Acta Applicandae Mathematicae, Vol. 79, Iss. 1-2, 2003-10 ,pp. :
Measuring precision in bioassays: Rethinking assay validation
STATISTICS IN MEDICINE, Vol. 37, Iss. 4, 2018-02 ,pp. :
Concordance of Noncarcinogenic Endpoints in Rodent Chemical Bioassays
RISK ANALYSIS, Vol. 35, Iss. 6, 2015-06 ,pp. :