Enhancement of the Antitumour Activity for the Synthesised Dodecylcysteine Surfactant using Gold Nanoparticles

Author: Azzam E.  

Publisher: Springer Publishing Company

ISSN: 1097-3958

Source: Journal of Surfactants and Detergents, Vol.11, Iss.3, 2008-09, pp. : 195-199

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Abstract

In this paper, the surfactant dodecylcysteine hydrochloride was synthesised. The surface parameters of the synthesised surfactant were studied using a surface tension technique. The surface parameters show a good surface activity of the prepared surfactant in aqueous solution. The self-assembling behaviour of the synthesised surfactant comparing with that of cysteine compound on the prepared gold nanoparticles was confirmed using transmission electron microscope (TEM) measurements. The effect of self-assembling of this surfactant on the size of gold nanoparticles was studied using TEM images. The antitumour activity of the prepared surfactant without and with the gold nanoparticles was investigated. The results show that the antitumour activity of the prepared surfactant was enhanced with the presences of the gold nanoparticles.

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