Preparation of Benzenesulfonic Acid Functionalized Magnetic Silica Nanoparticles for Extraction of Glycopeptide Antibiotics from Water

Author： Deng Xiaojuan Yao Pei Ding Guosheng Lin Kui

Publisher： American Scientific Publishers

ISSN： 1947-2935

Source： Science of Advanced Materials, Vol.5, Iss.8, 2013-08, pp. : 1032-1040

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Benzenesulfonic acid functionalized magnetic silica nanoparticles (BSAF-MSNPs) were prepared based on three-step reactions of coprecipitation, sol-gel polymerization, and silanization. The structure and properties of the synthesized magnetic nanoparticles were studied by transmission electron microscopy (TEM), fourier transform infrared spectrometry (FT-IR), and vibrating sample magnetometer (VSM). These nanoparticles were applied as adsorbent for extraction of glycopeptide antibiotics including vancomycin (VCM) and norvancomycin (NVCM) from water followed by high performance liquid chromatography (HPLC) analysis. The negative charges on the surface of the BSAF-MNPs promote strong electrostatic interaction with cationic compounds to exhibit selective and efficient extraction capacity. The hydrophobic interaction between the phenyl groups also plays a supplementary role. In addition, the superparamagnetism allows for easy manipulation of the nanoparticles under an adscititious magnet. Therefore, the adsorbent can be simply and quickly separated from the aqueous solution during the extraction procedure. Different parameters influencing the extraction efficiency including amount of adsorbent, extraction conditions, and desorption conditions were optimized. This study highlights the utility of prepared BSAF-MSNPs for rapid, selective, and efficient extraction of trace glycopeptide antibiotics from water samples.