Author: Zhang Mingzi M Su Xiaoyun Ang Ee Lui Zhao Huimin
Publisher: Future Science
ISSN: 2048-9145
Source: Pharmaceutical Bioprocessing, Vol.1, Iss.2, 2013-06, pp. : 179-196
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Abstract
Biocatalysts are increasingly employed as more efficient and environmentally safer alternatives to traditional chemical catalysts in the manufacturing of fine chemicals. This is driven by advances in recombinant DNA technology, protein engineering and bioinformatics, all of which are critical in the discovery, tailoring and optimization of enzymes for industrial processes. In this article we review these key technological innovations, as well as highlight the strategic application of these tools in the development of biocatalysts in the production of advanced pharmaceutical intermediates.
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