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Prediction of metabolic drug clearance in humans: In vitro–in vivo extrapolation vs allometric scaling

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In vitro–in vivo extrapolation of hepatic clearance: Biological tools, scaling factors, model assumptions and correct concentrations

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Correlation of the intrinsic clearance of donepezil (Aricept) between in vivo and in vitro studies in rat, dog and human

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In vitro–in vivo extrapolation of hepatic clearance involving active uptake: Theoretical and experimental aspects

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