The self-assembly and lyotropic mesomorphism of riboguanylic acids (GMP)

Author: Gottarelli G.   Proni G.   Spada G.P.  

Publisher: Taylor & Francis Ltd

ISSN: 0267-8292

Source: Liquid Crystals, Vol.22, Iss.5, 1997-05, pp. : 563-566

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Abstract

The three isomeric guanylic acids (5'-GMP, 3'-GMP and 2'-GMP) and the 3':5'-cyclic derivative (cGMP) form, in water solution, left-handed columnar aggregates which, at higher concentration, pack to give left-handed cholesteric mesophases. The self-assembly process and liquid crystal formation are discussed in relation to the behaviour of the 2'-deoxy analogues.