Author： Farina Angela Ferranti Carolina Marra Carolina
Publisher： Taylor & Francis Ltd
ISSN： 1478-6419
Source： Natural Product Research, Vol.20, Iss.3, 2006-03, pp. : 247-252
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Abstract
In this article we report an improved total synthesis of resveratrol, increasing the overall yield from 22 to 71%. The synthesis reported in our previous publication was made up of two fundamental steps: a Wittig reaction and a Heck coupling. Here we studied these steps separately to increase the individual yields. The yield of the Wittig reaction was increased up to 98%; however, we could not find better reaction conditions for the Heck coupling than those reported in the previous article.
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