Author： Mallik Asok K.
Publisher： Taylor & Francis Ltd
ISSN： 1751-8253
Source： Green Chemistry Letters and Reviews, Vol.5, Iss.3, 2012-09, pp. : 321-327
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Abstract
A convenient, eco-friendly, and efficient method for synthesis of bis(3-indolyl)methanes by the reaction of indoles with various aromatic aldehydes “on-water has been developed. The attractive features of this method are that in cases of aldehydes which are easily oxidized to acids, no external catalyst is necessary while in other cases a trace amount (ca. 5 mol%) of commercially available and inexpensive catalyst benzoic acid is sufficient to give good to excellent yield of products.
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