Therapeutic Efficacy of Zinc Sulphate Used in Clustered Model Treatment in Alleviating Zinc Deficiency in Cattle and Its Effect on Hormones, Vitamins and Production Parameters

Author： Sharma M. Joshi C.

Publisher： Springer Publishing Company

ISSN： 0165-7380

Source： Veterinary Research Communications, Vol.29, Iss.7, 2005-10, pp. : 609-628

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Abstract

A survey was conducted in 10 districts of northern India. Significant deficiency of zinc was observed in soil, fodders and (cattle) serum samples. The animals showed typical signs of zinc deficiency, namely stiff gait, swelling of hocks and knees, subcutaneous fluid accumulation, rough coat, etc. of variable intensity. A clustered model therapeutic trial was conducted and zinc-deficient cattle were divided into three groups. Group A was provided with mineral mixture containing zinc sulphate. Group B was given mineral mixture without zinc sulphate and group C was given no mineral mixture. Significant improvement (p < 0.01)="" was="" observed="" in="" the="" haemoglobin="" (hb),="" total="" white="" blood="" cells="" (wbc)="" and="" total="" erythrocyte="" count="" (tec)="" levels="" at="" the="" 7th="" day="" of="" treatment="" in="" the="" animals="" of="" group="" a.="" significant="" improvement="" in="" enzyme="" serum="" alkaline="" phosphatase="" (sap)="" was="" observed="" in="" group="" a="" animals="" at="" the="" 7th="" day,="" while="" improvement="" in="" asparatate="" aminotransferase="" (ast),="" alanine="" aminotransferase="" (alt)="" and="" ceruloplasmin="" (cp)="" was="" observed="" after="" 21="" days="" of="" treatment.="" regarding="" hormones,="" significant="" improvement="" was="" observed="" in="" thyroxine="">₃) and triiodothyronine (T₄), oestrogen and progesterone in group A animals within 14 days of treatment. The values of vitamin A showed a highly significant (p < 0.01)="" improvement="" within="" 7="" days="" of="" treatment="" in="" group="" a="" animals="" and="" that="" of="" vitamin="" e="" on="" the="" 21="" st="" day="" of="" treatment.="" the="" milk="" yield="" of="" lactating="" cattle="" and="" body="" weight="" of="" growing="" calves="" in="" group="" a="" showed="" highly="" significant="">p < 0.01)="" increases="" at="" about="" 14="" and="" 30="" days,="" respectively.="" it="" is="" concluded="" that="" zinc="" sulphate="" supplementation="" is="" highly="" effective="" in="" alleviating="" zinc="" deficiency="" and="" improving="" various="" biochemical="" and="" production="" parameters="" in="" cattle.="" the="" clustered="" model="" treatment="" provides="" a="" better="" indicator="" of="" the="" most="" limiting="" element="" under="" field="" conditions="" where="" simultaneous="" deficiency="" of="" various="" minerals="" is="" prevalent.="">