

Author: Siegel J.
Publisher: Springer Publishing Company
ISSN: 0001-8244
Source: Behavior Genetics, Vol.27, Iss.6, 1997-11, pp. : 557-563
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Abstract
High- and low-sensation seeking behaviors in human and cat are shown to be correlated with visual evoked potential (VEP) augmenting and reducing, respectively. Demonstration of this relationship in RHA/Verh and RLA/Verh rats provides a heuristic animal model with which to investigate the physiological and genetic basis of this relationship. Recent work is described which shows that VEP augmenting and reducing is a true cortical phenomenon and not merely a reflection of differences occurring at the thalamus. Recent evidence is discussed that suggests the role of diffuse subcortical monoaminergic projections to the cortex as the neurochemical basis for sensation seeking behaviors controlled by prefrontal and limbic cortex and perhaps the correlated VEP augmenting/reducing responses recorded from the posterior cortex.
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