Stereoselective reduction of ketones by Daucus carota hairy root cultures

Author: Caron Dave  

Publisher: Springer Publishing Company

ISSN: 0141-5492

Source: Biotechnology Letters, Vol.27, Iss.10, 2005-05, pp. : 713-716

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Abstract

Reduction of acetophenone by Daucus carota</i> hairy root cultures afforded (S</i>)-phenylethanol in high yield (96%) and excellent enantiomeric excess (ee ≥ 98%). Aromatic ketones, keto esters, and a simple aliphatic ketone were reduced with good stereoselectivity (ee = 62–98%) and moderate to high chemical yields (25–90%).