The [(methyloxy)imino]methyl moiety (MOIMM) in the design of a new type of -adrenergic blocking agent

Author： Balsamo A.   Macchia M.   Martinelli A.   Rossello A.  

Publisher： Elsevier

ISSN： 0223-5234

Source： European Journal of Medicinal Chemistry, Vol.34, Iss.4, 1999-04, pp. : 283-291

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

Synthesis and -adrenergic properties of (E)-N-[3-(alkylamino)-2-hydroxypropylidene](methyloxy)amines substituted with an aromatic group on their [(methyloxy)imino]methyl moiety (MOIMM): an investigation into the biopharmacological effects of an aryl substitution in the class of MOIM -blocking drugs

By Balsamo A.   Breschi M.   Chiellini G.   Favero L.   Macchia M.   Martinelli A.   Martini C.   Rossello A.   Scatizzi R.  

European Journal of Medicinal Chemistry, Vol. 30, Iss. 10, 1995-01 ,pp. : 743-755

Elsevier

Access to resources Recommend Favorite

New chiral methyloxyiminomethyl (MOIM) -adrenergic antagonists. (S)- and (R)-N-[3-(alkylamino)-2-hydroxypropylidene](p-chlorophenylmethyloxy)amines as probes for determining enantiomeric specificity in the class of MOIM-type -adrenergic blocking agents

By Balsamo A.   Breschi M.   Chiellini G.   Macchia B.   Macchia M.   Manera C.   Sacca P.   Scatizzi R.  

European Journal of Medicinal Chemistry, Vol. 31, Iss. 3, 1996-01 ,pp. : 199-206

Elsevier

Access to resources Recommend Favorite

Synthesis and 2 -adrenergic activity of 2-[(methyleneamino)oxy]-N-(guanidino)ethaneimines. A biososteric replacement of the aryl of guanabenz-type benzylideneaminoguanidine 2 -agonists with the [(methyleneamino)oxy]methyl moiety (MAOMM)

By Balsamo A.   Gentili D.   Macchia M.   Martinotti E.   Rossello A.   Scatizzi R.  

European Journal of Medicinal Chemistry, Vol. 31, Iss. 9, 1996-01 ,pp. : 713-716

Elsevier

Access to resources Recommend Favorite

Pharmacological effects of an aldehyde type / -adrenoceptor blocking agent with vasodilating properties

By Chiu C.-C.   Lin Y.-T.   Tsai C.-H.   Liang J.-C.   Chiang L.-C.   Wu J.-R.   Chen I.-J.   Yeh J.-L.  

General Pharmacology, Vol. 34, Iss. 6, 2000-06 ,pp. : 391-400

Elsevier

Access to resources Recommend Favorite

Conformationally restrained -blocking oxime ethers. 3. Synthesis and -adrenergic antagonistic activity of diastereomeric anti and syn 2-(5'-(3'-methyl)isoxazolidinyl)-N-alkylethanolamines

By Breschi M.   Macchia M.   Manera C.   Micali E.   Nardini C.   Nencetti S.   Rosello A.   Scatizzi R.  

European Journal of Medicinal Chemistry, Vol. 31, Iss. 2, 1996-01 ,pp. : 159-163

Elsevier

Access to resources Recommend Favorite