Author: Kooistra Bauke
Publisher: Springer Publishing Company
ISSN: 1068-9265
Source: Annals of Surgical Oncology, Vol.16, Iss.2, 2009-02, pp. : 281-284
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Abstract
Fine-needle aspiration (FNA) of breast lesions provides indeterminate (C1, C3, and C4) diagnoses in a high proportion of cases. The aim of the present study was to retrospectively determine whether repeat FNA or core needle biopsy (CNB) most frequently provides a correct and more conclusive diagnosis. All patients who had an indeterminate primary FNA followed by repeat FNA or CNB within 1 month from 1992 to 2007 were included. FNA was diagnosed as C1–C5; CNB was diagnosed as B1–B5. Improvement in preoperative diagnosis by repeat FNA or CNB was defined as C2/B2 in benign lesions, C3/B3 in premalignant lesions, C4/B4 or C5/B5 in malignant lesions where primary FNA was C1, and C5/B5 in malignant lesions where primary FNA was C3 or C4. Among 255 eligible cases, CNB improved the preoperative diagnosis more often than did repeat FNA (78.0% vs. 54.8%, odds ratio = 2.9, P</i> < .001). when="" corrected="" for="" patient="" age,="" appearance="" on="" mammogram="" (mass="" or="" not),="" clinical="" findings="" (palpable="" or="" not),="" tumor="" size,="" and="" aspiration="" mode="" (freehand="" vs.="" image="" guided),="" this="" difference="" slightly="" increased="" (odds="" ratio =" 3.0,"></ .001).>P</i> = .001). CNB should be performed after an indeterminate FNA of a breast lesion to obtain a reliable and clear preoperative diagnosis.
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