Substrate Specificity of Rhomboid Intramembrane Proteases Is Governed by Helix-Breaking Residues in the Substrate Transmembrane Domain

Author： Urban S. Freeman M.

Publisher： Elsevier

ISSN： 1097-2765

Source： Molecular Cell, Vol.11, Iss.6, 2003-06, pp. : 1425-1434

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

Structural comparison of substrate entry gate for rhomboid intramembrane peptidases

By Lazareno-Saez Christelle Brooks Cory L. Lemieux M. J.

Biochemistry and Cell Biology, Vol. 89, Iss. 2, 2011-04 ,pp. : 216-223

NRC Research Press

Access to resources Recommend Favorite

Altered Specificity Mutations Define Residues Essential for Substrate Positioning in Xanthine Dehydrogenase

By Glatigny A. Hof P. Romão M.J. Huber R. Scazzocchio C.

Journal of Molecular Biology, Vol. 278, Iss. 2, 1998-05 ,pp. : 431-438

Academic Press

Access to resources Recommend Favorite

Influence of Proline Residues in Transmembrane Helix Packing

By Orzaez M. Salgado J. Gimenez-Giner A. Perez-Paya E. Mingarro I.

Journal of Molecular Biology, Vol. 335, Iss. 2, 2004-01 ,pp. : 631-640

Elsevier

Access to resources Recommend Favorite

Substrate preference is altered by mutations in the fifth transmembrane domain of Ptr2p, the di/tri-peptide transporter of Saccharomyces cerevisiae

By Hauser Melinda Kauffman Sarah Naider Fred Becker Jeffrey

Molecular Membrane Biology, Vol. 22, Iss. 3, 2005-05 ,pp. : 215-227

Informa Healthcare

Access to resources Recommend Favorite

Identification of Residues 286 and 289 as Critical for Conferring Substrate Specificity of Human CYP2C9 for Diclofenac and Ibuprofen

By Klose T.S. Ibeanu G.C. Ghanayem B.I. Pedersen L.G. Li L. Hall S.D. Goldstein J.A.

Archives of Biochemistry and Biophysics, Vol. 357, Iss. 2, 1998-09 ,pp. : 240-248

Elsevier

Access to resources Recommend Favorite