Validation Study of a Semi-Automated Program for Quantification of Atherosclerotic Burden

Author: Choi Brian G.   Novoselsky Constantin A.   Vilahur Gemma   Viles-Gonzalez Juan F.   Zafar M. Urooj   Ibanez Borja   Fuster Valentin   Badimon Juan J.  

Publisher: Informa Healthcare

ISSN: 1097-6647

Source: Journal of Cardiovascular Magnetic Resonance, Vol.9, Iss.3, 2007-05, pp. : 615-620

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Abstract

Practical implementation of cardiovascular magnetic resonance (CMR) for the noninvasive screening of atherosclerosis is limited by inter-and intra-observer variability and labor intensity of morphometric analysis by manual planimetry (MANU). We assessed the hypothesis that a semi-automated quantification program (AUTO) for CMR would be faster and more accurate than MANU without loss of reliability. In the analysis of carotid atherosclerosis in asymptomatic hypercholesterolemic patients (n = 17), AUTO was superior to MANU in speed and histopathologic correlation without significant differences in inter-and intra-observer variability. Implementation of AUTO may facilitate CMR for the screening of the burden of atherosclerotic disease.

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