Activity-based exposure comparisons among humans and nonclinical safety testing species in an extensively metabolized drug candidate

Author： Zhu Xiaochun   Slatter J. Greg   Emery Maurice G.   Deane Molly R.   Akrami Anna   Zhang Xiping   Hickman Dean   Skiles Gary L.   Subramanian Raju  

Publisher： Informa Healthcare

ISSN： 1366-5928

Source： Xenobiotica, Vol.43, Iss.7, 2013-07, pp. : 617-627

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

Abundance- and Activity-Based Proteomics in Platelet Biology

By  

Current Proteomics, Vol. 8, Iss. 3, 2011-10 ,pp. : 216-228

Bentham Science Publishers

Access to resources Recommend Favorite

Evaluation of clinical colon carcinoma using activity-based proteomic profiling

By Zhang Melissa  

Clinical Proteomics, Vol. 1, Iss. 3-4, 2004-09 ,pp. : 301-311

Humana Press, Inc

Access to resources Recommend Favorite

Development of Activity-based Cost Functions for Cellulase, Invertase, and Other Enzymes

By Stowers Chris   Ferguson Elizabeth   Tanner Robert  

Applied Biochemistry and Biotechnology, Vol. 147, Iss. 1-3, 2008-03 ,pp. : 107-117

Humana Press, Inc

Access to resources Recommend Favorite

Studies on Plant-Pathogen Interactions Using Activity-based Proteomics

By  

Current Proteomics, Vol. 7, Iss. 4, 2010-12 ,pp. : 328-336

Bentham Science Publishers

Access to resources Recommend Favorite

Prediction of fraction metabolized via CYP3A in humans utilizing cryopreserved human hepatocytes from a set of 12 single donors

By Desbans C.   Hilgendorf C.   Lutz M.   Bachellier P.   Zacharias T.   Weber J. C.   Dolgos H.   Richert L.   Ungell A.-L.  

Xenobiotica, Vol. 44, Iss. 1, 2014-01 ,pp. : 17-27

Informa Healthcare

Access to resources Recommend Favorite